Bioclinic Naturals IB Care 60 Softgels

Relieves Abdominal Pain and Discomfort Associated with IBS

Benefits

• Provides clinically effective amounts of peppermint, caraway, and oregano oils at proven dosages
• Potent amounts of active components: 50% menthol (peppermint), 60% phenol (oregano), and 50% carvone (caraway)
• Enteric coating improves efficacy, allowing for antispasmodic effect in gastric and upper intestinal tissues
• Research confirms that peppermint oil is more effective and better tolerated when protected from stomach acid
• Enteric coating also reduces adverse effects and peppermint taste11

IB Care contains enterically coated peppermint, oregano, and caraway oils, all shown to have benefit for diverse gastrointestinal disturbances. Peppermint oil is known to influence gastric motility, accelerating early gastric emptying with an antispasmodic effect on the stomach.1 It also increases the relaxation time of the pyloric valve, decreases the resting pressure of the lower esophageal sphincter, and has synergistic benefit when combined with caraway oil, producing smooth muscle relaxation in the stomach and duodenum.2, 3 Oregano oil has demonstrated antimicrobial effects against H. pylori, the primary cause of peptic ulcer disease and dyspepsia, as well as other GI pathogens.4, 5

Clinically, enterically coated preparations of these oils have demonstrated benefits in a number of clinical trials. Improvement has been shown for dyspepsia and symptoms such as pain, heaviness, and abdominal pressure in controlled trials, regardless of H. pylori status and even in those with significant epigastric pain.6, 7, 8 Additionally, enteric coated peppermint oil demonstrated clinical efficacy in a number of trials for irritable bowel syndrome, showing improvement in the majority of participants, and in both children and adults.9, 10

References

1. Inamori M, Akiyama T, Akimoto K, et al. Early effects of peppermint oil on gastric emptying: a crossover study using a continuous real-time 13C breath test (BreathID system). J Gastroenterol. 2007 Jul;42(7):539-42.
2. Hiki N, Kurosaka H, Tatsutomi Y, et al. Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial. Gastrointest Endosc. 2003 Apr;57(4):475-82.
3. Micklefield G, Jung O, Greving I, May B. Effects of intraduodenal application of peppermint oil (WS(R) 1340) and caraway oil (WS(R) 1520) on gastroduodenal motility in healthy volunteers. Phytother Res. 2003 Feb;17(2):135-40.
4. Mahady GB, Pendland SL, Stoia A, et al. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res. 2005 Nov;19(11):988-91.
5. Force M, Sparks WS, Ronzio RA. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. 2000 May;14(3):213-4.
6. Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled double-blind equivalence study. Arzneimittelforschung. 1999 Nov;49(11):925-32.
7. May B, Köhler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther. 2000 Dec;14(12):1671-7.
8. May B, Kuntz HD, Kieser M, Köhler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung. 1996 Dec;46(12):1149-53.
9. Ford AC, Talley NJ, Spiegel BM, et al. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ. 2008 Nov 13;337:a2313.