Scientists have identified specific extracts from cruciferous vegetables — such as broccoli, cauliflower, cabbage and Brussels sprouts — that help maintain healthy hormone levels.1-11 Maintaining optimal hormone balance is essential to any anti-aging strategy. Triple Action Cruciferous Vegetable Extract combines some of these botanical extracts into the most comprehensive food-based, plant compilation for cell protection yet.
I3C (Indole-3-carbinol) and DIM (Di-indolyl-methane) favorably modulate estrogen metabolism and induce liver detoxification enzymes to help neutralize potentially harmful estrogen metabolites and xenoestrogens (estrogen-like environmental chemicals).12-16
Extracts of broccoli, watercress, and rosemary provide glucosinolates, isothiocyanates, carnosic acid, and carnosol — bioactive compounds that have a multitude of favorable effects on estrogen metabolism and cell division.17-20 Apigenin, a powerful plant flavonoid, is also added to the formula to boost cell protection, 21 while cabbage extract, a natural source of benzyl isothiocyanate (BITC), is included to maintain cell health.8, 22
Life Extension has combined its cruciferous vegetable complex with trans-resveratrol based on indications from published scientific literature that resveratrol may be the most effective compound for maintaining optimal health and promoting longevity.23 The whole grape extract contains a spectrum of polyphenols naturally found in red wine, such as proanthocyanidins, anthocyanins, and flavonoids.
References
- J Nutr. 2008 Dec;138(12):2379-85.
- J Cell Physiol. 2009 Apr;219(1):94-9.
- J Nutr Biochem. 2009 Mar;20(3):195-201.
- Eur J Cancer Prev. 2007 Dec;16(6):505-10.
- Int J Oncol. 2008 Aug;33(2):415-9.
- Chem Res Toxicol. 2012 Jan 13;25(1):61-73.
- Ann Oncol. 2012 Aug;23(8):2198-203.
- PLoS One. 2012;7(2):e32267.
- Mol Cell Endocrinol. 2012 Nov 5;363(1-2):74-84.
- Breast. 2012 Aug 6. [Epub ahead of print]
- Biopharm Drug Dispos. 2012 Nov 8. doi: 10.1002/bdd.1826. [Epub ahead of print]
- Biochem Pharm. 2002, 64;393-404.
- Toxicol Appl Pharm. 2001 Jul 15;174(2):146-52.
- In Vivo. 2006 Mar-Apr;20(2):221-8.
- Cancer Detect Prevent. 2004;28:72-9.
- Mol Carcinog. 2012 Mar;51(3):244-56.
- Carcinogenesis. 2002 Apr;23(4):581-6.
- Mol Cancer Ther. 2003 Oct;2(10):1045-52.
- Biosci Biotechnol Biochem. 2012;76(1):115-9.
- J Complement Integr Med. 2012 Jul 2;9(1):Article13.doi:10.1515/1553-3840.1611.
- J Clin Biochem Nutr.2009 May;44(3):260-5.
- Food Chem Toxicol. 2008 Jul;46(7):2358-64.
- ClinIntervAging. 2008;3(2):331-9.