Many B vitamins are used in the body individually or in combination with enzymes to help release energy from carbohydrates, fat, and protein. Vitamin B coenzymes are crucial to the metabolic pathways that generate the energy needed by every cell in the body. Because they are codependent in their metabolic activities, a deficiency of one B vitamin can affect optimal functioning of organ systems throughout the body.170
Niacin is the only B vitamin that can be synthesized in the liver from the amino acid tryptophan — on average, 1 mg of niacin can be synthesized from the ingestion of 60 mg of tryptophan.198-200 In its coenzyme forms, niacin is crucial to energy transfer reactions, particularly the metabolism of glucose, fat, and alcohol.201, 202 Niacin’s beneficial effects on blood lipids is well-documented.203-215
References available upon request.