NeuroScience AdreCor with Licorice Root 90 Capsules

Increases cortisol levels and provides non-glandular ingredients important for adrenal health, energy, wakefulness, and stress management* Key ingredientsGlycyrrhizic acid (from Licorice root extract): Glycyrrhetinic acid (metabolite of glycyrrhizic acid) binds 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2) to inhibit the breakdown of cortisol (1, 2).* L-histidine: Precursor to histamine. In the central nervous system, histamine plays an important role in the release of pituitary hormones and wakefulness (3). L-methionine: Precursor to S-adenosylmethionine (SAMe) (4). SAMe is directly involved in methylation processes including catecholamine synthesis (5). L-tyrosine: Precursor to catecholamines including dopamine, norepinephrine, and epinephrine. Rhodiola Rosea root extract (5% rosavins): Adaptogen that has been shown to reduce stress-induced effects (6, 7).* In a randomized, double-blind, placebo-controlled study, Rhodiola Rosea was shown to significantly improve mental fatigue and general well-being under stress (7).* Green tea leaf extract (Camellia sinensis) (65% EGCG): Epigallocatechin gallate (EGCG) is a polyphenol in green tea that provides antioxidant protection by its ability to scavenge free radicals and metal ions (8).* EGCG has been shown to increase resistance to fatigue in animal models (9).* Vitamins B and C: Active forms of pantothenic acid, niacin, B6, folate, B12, and C are important for the synthesis of adrenal hormones and neurotransmitters (10-14).* References van Gelderen C, et al. Hum Exp Toxicol. 2000;19(8):434-9. Chapman K, et al. Physiol Rev. 2013;93(3):1139-206. Krystal A, et al. Sleep Med Rev. 2013;17(4):263-72. Duncan T, et al. Mol Nutr Food Res. 2013;57(4):628-36. Mischoulon D and Fava M. Am J Clin Nutr. 2002;76(5):1158S-61S. Chiang H, et al. J Food Drug Anal. 2015;23(3):359-69. Spasov A, et al. Phytomedicine. 2000;7(2):85-9. Legeay S, et al. Nutrients. 2015;7(7):5443-68. Teng Y and Wu D. Pharmacogn Mag. 2017;13(50):326-31. Ragaller V, et al. J Anim Physiol Anim Nutr (Berl). 2011;95(1):6-16. Vrecko K, et al. Biochim Biophys Acta. 1997;1361(1):59-65. May J, et al. Brain Res Bull. 2013;90:35-42. Antoniades C, et al. Circulation. 2006;114(11):1193-201. Mattson M and Shea T. Trends Neurosci. 2003;26(3):137-46.